Rest has several meanings. See:

* rest (music), a pause in a piece of music.
* rest (object), a support for a musket or billiards or snooker cue.
* rest (physics), the relation between two observers.
* rest as action, to relax, see leisure; compare recreation.
* The reserves of the Bank of England.
* In software engineering, REST is an acronym for Representational State Transfer.
* ReST or reST also refers to the markup language reStructuredText.
* In chemistry a rest (abbreviated R) is a variable part of a molecule attached to a given core structure. See: functional group and side chain.