Edward Stafford, 2nd Earl of Wiltshire (April 7, 1470 - March 24, 1498/9) was an English nobleman.

He was the only child of John Stafford, 1st Earl of Wiltshire, and succeeded his father as earl in 1473 when he was 3 years old.

He was made a Knight of the Bath in 1475.

He married Margaret Grey, daughter of Edward Grey, Viscount Lisle, but they had no children. The earldom of Wiltshire became extinct on his death, though it was re-created for his cousin Henry Stafford, 1st Earl of Wiltshire.

Wiltshire, Edward Stafford, 2nd Earl of
Wiltshire, Edward Stafford, 2nd Earl of
Wiltshire, Edward Stafford, 2nd Earl of
Wiltshire, Edward Stafford, 2nd Earl of